Genomic Sequencing of Ranaviruses Isolated from Edible Frogs ( Pelophylax esculentus )

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Genomic Sequencing of Ranaviruses Isolated from Edible Frogs (Pelophylax esculentus)

Ranaviruses were isolated from wild edible frogs (Pelophylax esculentus) during epizootics in Denmark and Italy. Phylogenomic analyses revealed that these isolates are closely related and belong to a clade of ranaviruses that includes the Andrias davidianus ranavirus (ADRV), common midwife toad ranavirus (CMTV), Testudo hermanni ranavirus (THRV), and pike-perch iridovirus (PPIV).

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Ranaviruses (family Iridoviridae) were discovered serendipitously during an attempt to generate frog kidney cell cultures for the propagation of Lucke herpesvirus, an oncogenic herpesvirus [1]. Unexpectedly, some cultures displayed spontaneous cytopathic effect suggestive of a viral infection. Frog virus (FV)-1 and -2 were recovered from normal kidneys, whereas FV3, isolated from a frog with re...

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ژورنال

عنوان ژورنال: Genome Announcements

سال: 2017

ISSN: 2169-8287

DOI: 10.1128/genomea.01015-17